The Gut Microbiome: Where Collagen And The Immune System Meet

The Gut Microbiome: Where Collagen And The Immune System Meet

By now, it’s a familiar fact: Humans have more bacterial cells—a lot more—than human cells.

Bacteria live on the skin, in the nose and ears, and, most of all, in the gut.

Until recently, if most people thought about those bacteria at all, we tended to think of them as fairly separate from us. They help with digestion, but otherwise they stay on their side of the intestinal lining, and we stay on our side.

But, in fact, there is a lot of interaction between the body’s immune system and bacteria in the gut, otherwise known as our microbiota (the vast communities of bacteria present within our GI tract).

What’s more, researchers are now starting to uncover the critical role that collagen plays in protecting this delicate microbiome balance and the long-term implications it offers in sustaining optimal immune function as we grow older.

The Importance Of Your Intestinal Wall

“A huge proportion of our immune system (about 80%) is actually in our GI tract,” says Dr. Chad Walding, Doctor of Physical Therapy and NativePath Co-Founder.

Therefore, you can think of your intestinal tract as the “central immunity hub” of the body and its surrounding lining as the protective barrier.

The intestinal wall not only functions to allow nutrients to be properly absorbed and utilized by the body, but it also prevents lethal pathogens from passing through and infecting the blood.

But how exactly does it happen? This is the question that Dr. Walding answers by taking a closer look at what our gut lining is composed of.

“The efficiency at which our intestines are able to allow nutrients to pass through to the rest of the body while stopping most harmful bacteria from doing the same all comes down to collagen,” says Dr. Walding.

Here’s Where Collagen Comes In

Collagen is a special type of structural protein that is full of helpful amino acids. In fact, it’s the most abundant protein in the body; making up 90% of your connective tissue and organic bone mass, 70% of our skin, and as you’ve probably guessed - is the main component that makes up our intestinal lining.

From beginning to end the adult digestive tract is about 30 feet long - that's a lot to structure and a lot to regulate.

Fortunately, collagen's amino acid profile provides the necessary building blocks to maintain and repair the intestine for optimal immune function.

Here are the biggest immunity-supporting gut health benefits that collagen provides, according to science:

1.) Reduces the risk of digestive conditions


Collagen contains glycine, an amino acid which has been shown to have anti-inflammatory properties. Inflammation is the root cause of many autoimmune conditions and diseases, so preventing it should be a top priority.

2.) Supports the detoxification of pathogenic flora

Because collagen is a hydrophilic molecule, it has an attraction to water and acidic molecules, which aids the digestive process. When ingested, collagen surrounds itself with water and stomach acid as it moves through the GI tract, which assists the breakdown of other proteins and carbohydrates in the intestines.

Additionally, by holding water in the intestine, collagen helps move food through the GI tract more smoothly for faster (and more regular) excretion wastes and toxins.

3.) Helps prevent autoimmune conditions and leaky gut syndrome

Processed foods, lack of sleep, stress and use of antibiotics all affect the lining of the gut. Overtime they can cause it to become more permeable and to leak lethal substances through the intestinal wall which puts our immunity in serious danger.

This means that toxins, viruses and unfriendly bacteria can end up in the bloodstream instead of excreted - something experienced with leaky gut syndrome.

A leaky gut not only leaks toxins and bad bacteria, but also nutrients. A permeable gut lining can prevent vitamins and minerals in food from being absorbed properly.

“So regardless of how good your diet is, all of that goodness could literally go to waste if your gut lining isn’t as healthy as it should be,” says Dr. Walding.

Glutamine, one of the amino acids in collagen, has been identified as the key amino acid for preventing inflammation of the gut wall and healing leaky gut syndrome. It has been linked to inhibiting inflammation and oxidative stress associated with the opening of tight junctions in the connective tissue of the intestinal lining.

The Bottom Line: Healthy Immune Function Starts In The Gut

“Collagen literally seals and heals the gut - standing as our first line of defense when it comes to protecting our immunity and defending against unwanted illness,” Dr. Walding continues.

The protective cast collagen provides around our central immune hub allows for the optimal balance of beneficial gut bacteria to flourish. As a result, the microbiome can more effectively support the proper signaling and activity of immune cells.

By strengthening and rebuilding the gut wall, collagen also helps make it less permeable and more likely to retain key immunity-boosting nutrients from food.

In addition, collagen helps keep our intestines nice and flexible due to its elastic qualities, which helps to move food around and increase absorption further while speeding up bowel movements to pass toxic wastes more efficiently.

Despite the critical role collagen plays with our immunity and overall health, most adults are highly deficient - namely for two reasons:

  • Our body’s stop producing it. As we grow older, our body’s collagen production naturally begins to slow down resulting in a degenerative process affecting joints, bones, skin and our first line of defense against illness - our gut integrity.
  • Our modern diets lack it. While our ancestors consumed a collagen-rich diet, our modern eating habits don’t often include the same foods that civilizations before us did like bone marrow, fish skin, poultry cartilage, and animal organs such as hearts, livers, and eyes.

For these reasons, it’s important that we find an approach for getting more collagen in our diet that is practical and easy to stick to.

A Way Forward For Aging Adults: How To Close The “Immunity Gap” For Good

Here’s what aging adults need to know:

Overtime, things like antibiotics, stress, lack of sleep, excessive hygiene, medicine and indoor living all begin to mess with our balance of bacteria and create literal “gaps” within our intestinal lining.

As a result, the overall health of our gut declines which, as you’ve learned, severely comprises the ability of our immune system to function optimally.

What’s more, declining collagen levels as we age mean that the integrity of our microbiome is doubly at risk - subjecting older adults to suffering with poor immunity in the later years of our lifespan.

The good news is that clinical studies show collagen supplementation can not only bridge the gap in falling collagen levels, but also repair and strengthen the gut lining, allowing healthy bacteria to flourish so that the digestive system and immune system can thrive.

“We can’t avoid getting older but we can be proactive in the longevity of our own health - and there’s no better place to start than by bolstering our immunity using the power of collagen's tissue healing and sealing benefits,” says Dr. Walding.

This is exactly where a high-quality collagen supplement can make all the difference.

Supplementing with a premium collagen formula like NativePath Grass-Fed Collagen, which contains two targeted fiber types (type I & III), helps reinforce intestinal integrity to keep pathogens from seeping into our bloodstream.

As a result, collagen supplementation helps increase the absorption of immune-boosting nutrients from our diet to better maintain proper activity in immune cells while also encouraging the production of T-cell and B-cell immune factors.

“At NativePath, our collagen powder formula provides the same exact set of immune-modulating amino acids as food sources of collagen but has undergone a process called hydrolysis to break them down into shorter chains of proteins, thus making them more highly absorbable. This breakthrough in nutrition science allows the collagen to go to work within the body within an hour of ingestion,” says Dr. Walding.

Hydrolyzed collagen powder can be dissolved in hot or cold water and is odorless and tasteless, making it an easy (and virtually undetectable) addition to your morning coffee, tea, smoothies and more.

How to Choose the Best Collagen Peptide Supplement

Transparency is key when it comes to choosing a ‘real food’ collagen supplement.

The sustainability of NativePath’s ethical sourcing practices makes all the difference when it comes to quality assurance.

Each small batch formula is sourced from 100% grass-fed cattle raised naturally across free-range pastures in Brazil.

“After extensive research, we found Brazil to have some of the most impressive guidelines when it comes to raising bovine. Ranchers are restricted by law from adding specific supplements, additional hormones, or growth stimulants to their cattle. Brazil, in particular, is one of the leading producers of bovine product exports to the United States, and if that wasn’t enough, all products are also highly regulated and inspected by the USDA,” he continues.

Transparency is key when it comes to choosing a ‘real food’ collagen supplement.

The sustainability of NativePath’s ethical sourcing practices makes all the difference when it comes to quality assurance.

Each small batch formula is sourced from 100% grass-fed cattle raised naturally across free-range pastures in Brazil.

“After extensive research, we found Brazil to have some of the most impressive guidelines when it comes to raising bovine. Ranchers are restricted by law from adding specific supplements, additional hormones, or growth stimulants to their cattle. Brazil, in particular, is one of the leading producers of bovine product exports to the United States, and if that wasn’t enough, all products are also highly regulated and inspected by the USDA,” he continues.

“In line with our high standards, our grass-fed collagen peptide formula is manufactured here in the USA at a GMP (Good Manufacturing Practice) certified facility to offer the most pure, nutrient-dense collagen on the market.”

NativePath collagen is completely free from the top 10 allergens including gluten, soy, dairy and nuts and contains absolutely no sugars, artificial flavors, dyes or thickeners.

What’s more, every batch is lab-tested to ensure it is free from heavy metals, toxins and microbes with no solvents ever used in the process - yielding a collagen peptide supplement that is as close to ‘real food’ nourishment as you can get.

With 10 grams of grass-fed hydrolyzed collagen peptides per scoop, NativePath’s powerful daily formula can help keep you feeling your best, inside and out - no matter what life throws your way.

Mobilize Your Defenses With NativePath Grass-Fed Collagen And Get The Daily Immune & Vitality Support Needed To Protect Against Harmful Pathogens

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JONI. FERRARI - April 7, 2020

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JONI. FERRARI - April 7, 2020

I SENT A DETAILED MESSAGE AND INFO /WITH A REQUEST THAT YOU CALL ME. BACK !!
THANK YOU FOR ALL THE INFORMATION YOU HAVE UP LOADED ! IT IS WONDERFUL TO BE CLEAR ON WHAT A PRODUCT DOES AND HOW IT DOES IT ! WELL WORTH MY TIME READ THROUGH ALL THE PAGES ! GOD BLESS ……..

JONI. FERRARI - April 7, 2020

I SENT A DETAILED MESSAGE AND INFO /WITH A REQUEST THAT YOU CALL ME. BACK !!
THANK YOU FOR ALL THE INFORMATION YOU HAVE UP LOADED ! IT IS WONDERFUL TO BE CLEAR ON WHAT A PRODUCT DOES AND HOW IT DOES IT ! WELL WORTH MY TIME READ THROUGH ALL THE PAGES ! GOD BLESS ……..

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